Hello, help

System file explorer.exe infected virus. Any Solution ? What should i do ?
Format machine ?

Report from Bit-Defender
-----------------------------------
Virus: Name: Backdoor.Agobot.AGH,
File: c:\windows\system32\explorer.exe, Object:
c:\windows\system32\explorer.exe, Status: Infected, Action: Failed to
delete!, Server: ifcaweb

Your help is appreciated.
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