Vista is vulnerable as well - I think the malware exploited a vulnerability associated with a plug-in on a web browser and gained a trusted toe-hold on the system. Rest is history - a rouge RPC process was observed running as a System user and privs. You can imagine the frustration I was having - I had ZERO control over that process....
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Link to this comment: http://www.securityfocus.com/comments/newsbriefs/862/2725#2725